November 7, 2022

Even though we consume oxygen to live, about 2–3% of the inhaled oxygen is converted into what is known as Reactive Oxygen Species (ROS).
When ROS accumulate excessively in the body, they begin to attack cells, proteins, fats, and other cellular components. This process of cellular deterioration is called "oxidation," commonly referred to as "the rusting of the body."
To counteract ROS, the human body possesses an ability called antioxidant capacity, which neutralizes them. An imbalance between ROS and antioxidant capacity is known as oxidative stress.
Should we eliminate all ROS from the body?
You may often hear or read advice that recommend to “eliminate reactive oxygen species,” but this formulation is incorrect to begin with.
Some ROS play crucial roles in immune function, defense against infection, and physiological processes such as ovulation, fertilization, and cell division.
The most important point is maintaining a proper balance between ROS and antioxidant capacity.
It is known that oxidative stress increases in various organs and tissues with age. Oxidative stress has been implicated in neurological disorders like Alzheimer's and Parkinson's diseases, as well as chronic respiratory diseases like emphysema. However, the relationship between oxidative stress and intervertebral disc degeneration was relatively unknown until recently.
New research has revealed that increased oxidative stress contributes to the onset and progression of intervertebral disc degeneration.Furthermore, there are study results suggesting that as disc degeneration progresses, oxidative stress further increases, creating a vicious cycle. Conversely, it is known that low oxidative stress makes disc degeneration less likely to develop or progress.
To slow the progression of disc degeneration and prevent it in other areas, aim for a lifestyle that enhances antioxidant capacity:
• Ensure adequate rest
• Engage in regular, moderate physical activity
• Consume antioxidant-rich foods
By incorporating these habits, you can enhance your body’s antioxidant capacity and support long-term spinal health.
ILC International Low Back Pain Clinic Tokyo
Registered Dietitian: Takeshi Deguchi